Department of Nephrology, Kidney Transplant & 24/7 Advance Dialysis Unit

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Nephrology 

Best Nephrology Hospital in Lucknow 

Charak Hospital's nephrology department is staffed by talented and experienced nephrologists who perform kidney biopsy, SLED, plasmapheresis, and hemodiafiltration. Additionally, we perform kidney transplants. Charak Hospital provides hemodialysis and plasma dialysis (plasmapheresis). Charak Hospital also has catheterization laboratories.

The key conditions in a patient with a nephro disorder are

Chronic Kidney Disease (CKD)

It is sometimes referred to as Chronic Renal Disease. This might take months or years, and symptoms include feeling generally sick and losing appetite. When people with high blood pressure, diabetes, or a bloodline member with CKD are examined, they may be infected with this disease. A blood creatinine test can be used to diagnose CKD. The greater the creatinine levels, the lower the glomerular filtration rate, and so the kidney's capacity to filter waste materials decreases. According to international standards, this condition progresses through five phases based on glomerular filtration rate and protein levels in urine. Screening is crucial because there are medications that can delay CKD.

The important symptoms are:

  • Increased blood pressure due to an overload of fluids.
  • Accumulation of urea in urine.
  • Potassium accumulates in the blood, resulting in hyperkalemia.
  • Erythropoietin synthesis decreases, causing anemia.
  • Symptoms related to fluid overload may range from mild edema to pulmonary edema

 

Acute Kidney Failure

The kidney's role is to filter body fluids, particularly blood. Acute Kidney Failure occurs when the kidney's ability to function fails unexpectedly. During this time, fluid levels in the body may increase to dangerous levels. It might develop in a matter of hours or days. It is especially common in persons who have already been hospitalized and require extensive care.

The main symptoms are:

  • Decreased urine flow, albeit this may be typical at times.
  • Fluid retention causes swelling of the legs, ankles, and feet.
  • Drowsiness, weariness, difficulty breathing, and nausea.
  • Chest discomfort or pressure.

In some situations, it may cause a coma or convulsions.
This failure may also be discovered in a person while being treated for another condition.
 

Anemia of Chronic Kidney Disease 

Anemia in the kidney develops when the levels of EPO (erythropoietin), a hormone generated by healthy kidneys, decrease. EPO signals the bone marrow to create red blood cells, which transport oxygen throughout the body via the bloodstream.

The common symptoms include:

  • You appear pale

  • You're feeling fatigued.

  • You have a low appetite and get less sleep.

  • Not enough energy to complete your everyday tasks.

  • A faster heartbeat.

  • You feel short of breath or despondent.

  • It's more common if you have diabetes.

Diabetic Kidney Disease

Diabetes causes damage to tiny blood vessels. The kidney's glomeruli, or filters, are damaged. Because of this large volume, proteins are discharged into the urine. The body will retain more water and salt than is ordinarily required. It is also known as Diabetic Nephropathy. The initial symptom is high albumin levels in the urine. Albumin is the primary protein that flows from a damaged kidney. The disease can be divided into:

In microalbuminuria, the albumin leak is approximately 30 to 300 mg per day. This is sometimes referred to as incipient nephropathy.
Proteinuria occurs when more than 300 mg of albumin are leaked every day. It's also known as macroalbuminuria or overt nephropathy.
 

Symptoms Include:

  • Dry, itchy skin.

  • Cramps in the muscles and puffiness around the eyes.

  • Needing to pass urine more often than normal.

  • Weight loss.

Glomerular Kidney Disease 

This is also known as glomerulonephritis. The kidneys include tiny filters known as glomeruli, which collect electrolytes, toxins, and waste from the blood and expel them through urine. It could be a quick onset of inflammation or a chronic condition that develops gradually. If this occurs on its own, it is classified as primary glomerulonephritis, or secondary glomerulonephritis when combined with diabetes or lupus.

The common symptoms include:

  • The presence of blood in the stream causes pink or cola-colored urine.

  • Anaemia or renal failure.

  • Swelling in the face, feet, hands, and abdomen.

  • Excessive protein content causes foamy urine.


Hypertension 

Hypertension is a disorder affecting the elderly. Hypertension in certain younger children could be caused by an underlying hormonal imbalance, vascular abnormalities, or kidney illness. Secondary hypertension may be treatable. The following suggests that hypertension may be a result of an underlying issue.

  • Hypertension starts at a young age.

  • Froth in urine

  • Nocturia is the need to pass urine many times throughout the night.

  • Associated symptoms include acute sweating bouts, palpitations, extreme weariness, and weight loss.

  • Ultrasounds reveal undersized or uneven kidneys.

Secondary hypertension can be appropriately detected and treated using a variety of simple to complex tests, ensuring the prevention of problems such as heart disease, renal disease, and eye damage.


Charak Hospital offers comprehensive care for the examination and treatment of hypertension.

  • Have you checked your blood pressure yet?

  • Do you understand your risk for high blood pressure?

  • Do any or both parents have high blood pressure or kidney disease?

  • Do you have uncontrolled blood pressure?

  • Are you hypertensive at a young age?

  • Do you know that the kidneys regulate your blood pressure?

  • Be sensible, BP-sensible!

  • Learn more about hypertension and its management.

  • Visit the "Hypertension Clinic" at Charak Hospital.

Others 

1. Hematuria 

It refers to the presence of blood cells in the urine tract. In most circumstances, it is harmless. In other circumstances, it could be linked to excessive exercise, a kidney illness, cancer-related drugs, alport syndrome (a type of cancer disease in the glomeruli), or an enlarged prostate. If you notice blood in your urine, you should consult a doctor immediately. Always choose prevention over cure!!

Hemolytic Uremic Syndrome results from the aberrant breakdown of red blood cells. These cells destroy the kidneys' filtering system, causing kidney failure. It primarily affects youngsters during diarrhea.

The common symptoms include:

  • Abdominal discomfort.

  • Low platelet count.

  • Anemia, edema, and tiredness.

2. Renal cell carcinoma

It is a kidney malignancy. It develops when malignant cells are present in the linings of the kidney's tubules. It is frequent among adults. Symptoms include blood in the urine, flank pain (pain between the ribs and hips), and abdominal mass caused by excessive bloating. This condition is caused by our lifestyle choices, which include smoking, diabetes, hypertension, and obesity.

 

Kidney Transplant

 

Best Kidney Transplant Hospital in Lucknow 

 

Overview of Kidney Transplant

For those suffering from end-stage renal disease (ESRD), sometimes known as "kidney failure," kidney transplantation provides a glimmer of hope when the kidneys are unable to carry out vital tasks. In order to prolong the life of the recipient, who has failing kidneys, a healthy kidney from a living or deceased donor is transplanted into the recipient.

Renal transplant expertise is just one example of how Charak Hospital, a well-known brand in the Lucknow and Uttar Pradesh healthcare industry, is dedicated to providing top-notch medical care. Charak Hospital has become one of the most reputable kidney transplantation hospitals in Lucknow, renowned for giving kidney transplant recipients the best care possible by putting a strong emphasis on innovation, patient care, and medical developments.

Why Choose Charak Hospital for Kidney Transplant

We are aware of the potential effects kidney transplantation may have on our patients' and their families' lives. In keeping with this knowledge, we work hard to give each patient the finest care possible at every stage of the procedure. We are among the most reputable kidney transplant centers in Lucknow because of the following qualities:

Expert Transplant Team: With extensive experience in kidney transplantation and demonstrated skill in their respective professions, our kidney transplant team is made up of some of the most well-known transplant surgeons, nephrologists, urologists, anesthetists, and support personnel.

Modern Infrastructure: Designed specifically for kidney transplants, Charak Hospital features state-of-the-art infrastructure and cutting-edge technologies. With state-of-the-art operating rooms, specialized ICU, and sophisticated imaging centers, we make sure our patients get the best care possible.

All-inclusive Services: We provide a full range of services needed for different kinds of kidney transplants, including transplants from living or deceased donors, transplants that are ABO incompatible, and specialized kidney transplantation for children.

High-quality care: The cornerstones of our kidney transplant program are quality and patient safety. From evaluation through post-transplant follow-up, we guarantee the highest caliber of treatment by adhering to strict national & international standards.

Empathic Approach: We recognize that receiving a kidney transplant entails emotional and psychological difficulties in addition to medical ones. We take a compassionate stance by offering patients and their families support, direction, and counseling at every stage of the process.

 

Types of Kidney Transplant  Available At Charak Hospital Lucknow 

 

  • Adult kidney transplant
  • Typical kidney transplant near a relative
  • ABO Incompatible kidney transplant
  • Pediatric kidney transplant

 

Types of Diseases that may require Kidney Transplant 

End-stage renal disease is one condition that may necessitate a kidney transplant. Diabetes, also known as diabetic nephropathy, is the leading cause of end-stage kidney disease in India. Hypertension, chronic glomerulonephritis, and polycystic kidney disease are some of the other possible reasons.
 

1. Diabetes mellitus, particularly type 2 diabetes, is a disease that potentially require kidney transplantation due to its significant impact on renal function.

2. Uncontrolled high blood pressure, also known as hypertension, can cause kidney damage, necessitating kidney transplantation as a therapy option.


3. Chronic glomerulonephritis, which is defined by inflammation of the kidney's glomeruli, is one of the factors that can lead to end-stage renal disease and the need for a kidney transplant.

4. Polycystic kidney disease is a hereditary illness marked by the formation of cysts in the kidneys. When existing treatments fail to properly manage polycystic kidney disease, kidney transplantation may be necessary.
 

How do we facilitate finding for a kidney transplant donor?

A kidney transplant donor, living or deceased, is subjected to a thorough review, including cross-match testing, to determine the risk of hyper-acute rejection, with a positive result indicating a contraindication for renal donation or transplantation. In accordance with the Human Organs Transplant Act, our facility prioritizes live donors who are first-degree relatives. Deceased donor registration is possible, and the registered government organization efficiently facilitates the acquisition of kidneys from deceased donors, which can then be transplanted into unknown individuals suffering from chronic renal disease. Organ allocation is established using a grading system provided by authorities, and patients can register with the hospital to ensure a spot for transplantation. Kidneys from deceased donors come from unlucky victims of accidents or strokes.

Proper medicine administration and timing are critical to avoiding drug toxicity or inadequate doses, which can affect drug absorption and raise the chance of rejection. Patients may also take medications to treat diabetes and hypertension, as well as preventative medications to avoid infections, all of which are important components of post-transplant patient care.

Deceased-donor transplantation, a type of kidney replacement, entails obtaining kidneys from people who have died, usually as a result of accidents or strokes. These organs are subsequently distributed to unknown individuals in need via government-run institutions.

Living donor transplantation is the transplantation of a kidney from a healthy living donor, typically a first-degree relative, who voluntarily donates their kidney to a loved one in need. These donors go through a thorough evaluation and workup to verify that the donation is appropriate and safe.

Expanded criteria for the donor Expanded criterion donors (ECD) are dead donors who are either too elderly or have medical issues that make them unsuitable for transplantation. In some situations, ECD kidneys may be used for transplantation to improve the pool of available organs and the likelihood of a successful transplant.

Kidney Compatibility: Choosing the Best Match Kidney compatibility is an important element in transplantation, and the best match is determined by comparing the donor and recipient's human leukocyte antigen (HLA) compatibility. HLA testing, together with other parameters such as blood type compatibility, contributes to the likelihood of a successful transplant and a lower risk of rejection.

 

Pre and Post Kidney Transplant Comprehensive Care

Post-kidney transplant care, commonly known as kidney transplant aftercare, is an essential component of maintaining patients following transplantation. Patients at our center undergo regular follow-up, beginning with twice-weekly visits for four weeks, followed by weekly visits for the next four weeks, and then biweekly appointments for the next four months, for a total period of six months. Following this period, the frequency of follow-up appointments is often reduced to monthly visits, which are adjusted to each patient's specific needs. Patients must comprehend the essential investigations and stick to their hospital follow-up routine.

The second part of treatment care focuses on personal cleanliness, grooming, and infection-prevention activities. Patients should avoid working for two to three months, depending on their vocation. During the first month after transplantation, patients are advised to adopt considerable isolation, which includes having a separate room with an associated bathroom and keeping strict personal hygiene.

This includes showering twice a day and ensuring that no hair remains in the crotch or axilla. In terms of food safety, patients are advised to drink only reverse osmosis (RO) or distilled water and eat freshly cooked meals, avoiding stale food.
Maintaining a clean and safe atmosphere is critical, and patients are advised to use air conditioners or air purifiers in their rooms. Anyone participating in patient care should use hand sanitizer before and after handling the patient. Furthermore, oral care requires frequent usage of mouthwash.

Patients should not return to work for at least three months after transplantation. They may then progressively shift to less physically demanding tasks, such as office work. However, it is critical to limit exposure to public transit, children, and huge crowds because the danger of contamination and illness increases dramatically.

Advance Services Available 

  • 24×7 Dialysis

  • Continuous Renal Replacement Therapy

  • 24×7 Nephrologist

  • Kidney transplant experts

  • 24×7 Dedicated ICU

 

Kidney Transplant Helpline  Number:     +91-9919040000

 

Department  Of  Dialysis 

 

The most advanced and safe dialysis center in Lucknow 

 

In the field of dialysis, Charak Hospital has established a precedent. We can provide the highest-grade dialysis that flawlessly satisfies international requirements because we are outfitted with top-notch technology.

What is dialysis? 

The kidneys filter your blood, eliminating waste and excess fluid. This trash is discharged as urine. The kidneys also regulate blood pressure and the quantities of chemical components in the body. End-stage renal failure is when the kidneys perform fewer than 15% of their normal function.

When the kidneys fail, dialysis takes over their function. It is a treatment that involves filtering and purifying blood over a semi-permeable membrane. It also aids in the maintenance of proper body fluid and salt balance. Without dialysis, waste materials and salts collect in the blood, which can harm other organ systems.
 

What are the different types of dialysis?

Hemodialysis: Hemodialysis is the most common type of dialysis. This method filters waste and excess fluid from the blood using a dialyzer (artificial kidney) and dialysate (water). The blood is withdrawn from the body, filtered by a machine, and then returned to the body. It is done using a hemodialysis machine.
 

Hemodiafiltration: This method combines the advantages of hemodialysis and hemofiltration. It is comparable to traditional hemodialysis but requires a substantial amount of replacement fluid. Hemodiafiltration removes uremic toxins more effectively and may provide benefits for anemia, inflammation, and oxidative stress reduction. Recent studies suggest improved patient survival with HDF.

Continuous renal replacement therapy (CRRT): When a patient has acute renal failure, this therapy is applied. A CRRT machine is used for the task. The CRRT modalities that are frequently employed are continuous hemodialysis, continuous hemofiltration, and continuous hemodiafiltration. Though replacement fluid is also needed, this procedure is comparable to hemodialysis. Usually, this process takes between 12 and 48 hours to complete.

Peritoneal dialysis (PD): A peritoneal dialysis catheter is surgically implanted into your belly during this procedure. Your peritoneum, a semipermeable membrane in your abdomen, serves as a filter in this process. Dialysate is a fluid that is pumped into your abdomen during therapy. After it absorbs waste and extra fluid from your blood, it is drained and disposed of.

 

Why choose Charak Hospital for your dialysis needs? 

The highest standards of quality: Charak Hospital has developed methods to meet and maintain worldwide standards, with an emphasis on every last detail of quality. To provide the best RO water, we have a state-of-the-art double RO water treatment plant and a loop water distribution system.
Patients undergoing hemodialysis are subjected to substantial weekly water intakes (between 300 and 600 liters), mostly from dialysate. Therefore, the quality of the water is an essential factor in preventing endotoxin, bacterial, and chemical pollutants that could endanger the health of hemodialysis patients.

At Charak Dialysis Center, we use a high-grade double reverse osmosis (RO) system with a loop RO distribution system to purify the water and provide our patients with effective hemodialysis using ultra-pure water (<0.1 colony forming units/ml, 2000 times fewer than AAMI standard limits). In compliance with the guidelines set forth by the AAMI (Association for the Advancement of Medical Instrumentation), we conduct routine full-panel water testing to guard against chemical, bacterial, and endotoxin contamination of dialysate water.

Strict Measures to Control Infection: Patients undergoing dialysis are vulnerable and prone to various illnesses. To ensure that all potential sources of infection are properly treated and that our patients receive the safest type of dialysis, hospital infection control teams constantly monitor our dialysis units.
Every instance involves a careful adherence to universal precautions for infection control. Dialysis patients who may have respiratory infections are segregated with different equipment and personnel due to the recent COVID-19 epidemic. Due to the high contagiousness of HIV, Hepatitis B, and Hepatitis C, patients with blood infections are segregated and given dialysis. Dialysis personnel from the positive area do not visit patients in the negative area. Every member of the staff in the dialysis department has also had a hepatitis B vaccination. The linen is doubly autoclaved and disposed of in a red bag.

Ever since we implemented the single-use dialyzer and tubing policy, our cross-infection rates have been zero. At our dialysis unit, we have state-of-the-art air purifiers to avoid airborne diseases. At our unit, hemodialysis supplies (on and off kits, heparin gloves) are customized for each patient.

Dializer Policy: Strict Single Use Only: Reusing dialysis machines for hemodialysis has long been done because of the supposed financial advantages. However, using a dialyzer more than once increases the risk of health problems from exposure to germicides. Reusing dialyzers has a high mortality risk, as shown by numerous large observational studies that have compared single-use and reused dialyzers.
The best alternative now that dialyzers are less expensive and technology is advancing is to implement a single-use dialyzer policy. Patients benefit from single-use goods because they lower their risk of cross-contamination, exposure to germicides, and usage of denatured blood products. A policy of single usage increases the elimination of toxins, making patient safety higher. Our first concern at Charak Hospital is patient safety. Our facility offers the best dialysis care possible to our patients by enacting a single-use dialyzer policy.

Supervision of nephrologists for every patient and every shift: Our skilled nephrologists give each and every one of our dialysis patients the best individual attention. Our guiding principles are individualized care and tailored dialysis.
Hemodialysis patients are typically required to endure four-hour sessions three times a week, depending on the patient's dialysis prescription. To prevent difficulties, it needs to be closely monitored and closely controlled.

Hemodialysis and hemodiafiltration services are available around the clock at Charak Hospital, and nephrologists are on staff 24/7. For improved outcomes, we give each patient a customized dialysis prescription. To ensure that dialysis is both safe and efficient for you, our highly skilled hemodialysis professionals work around the clock. Throughout the process, our skilled nursing team members provide individualized care and constant vital sign monitoring. Every patient has a personal dialysis technician or nurse assigned to them.
 

Scope Of Services 

  • Renal Transplant
  • Renal Biopsy 
  • Seropositive Dialysis 
  • Seronegative Dialysis
  • Permcath Insertion in ESRD patient 
  • AVR Fistula by specialist 
  • Advanced dialysis unit with Peritoneal and Nocturnal, SLED

 

Dialysis Helpline  Number:     +91-9919040000

 

 

Frequently Asked Questions 

The Nephrology Department at Charak Hospital provides services including diagnosis and treatment of kidney diseases, kidney transplant evaluations, and a 24/7 Advanced Dialysis Unit for patients requiring regular dialysis sessions.

Potential kidney transplant recipients are evaluated based on medical criteria, including the severity of their kidney disease, overall health, the presence of any conditions that may affect transplant success, and the availability of a suitable donor.

The process includes a thorough medical evaluation, identification of a compatible donor (living or deceased), surgery by specialized surgeons, and post-transplant care to manage potential complications and prevent organ rejection.

The 24/7 Advanced Dialysis Unit operates around the clock, providing flexible dialysis schedules to accommodate patients' needs and preferences. This ensures that patients receive timely treatment, whether for routine dialysis or emergency care.

Access to 24/7 dialysis means patients can receive treatment at convenient times, reducing the need for hospital admissions and improving quality of life. It also ensures immediate medical attention in case of acute kidney failure or emergency dialysis needs.

 Yes, Charak Hospital supports kidney transplants from living donors, provided the donor is a suitable match and the transplant is deemed safe for both the donor and recipient.

After a kidney transplant, patients are closely monitored for signs of organ rejection and any complications. Follow-up includes regular visits to the hospital, blood tests, and medication adjustments to ensure the transplant functions properly.

Charak Hospital offers psychological support to patients undergoing kidney transplantation. This includes counseling to help manage the stress and anxiety associated with the process, ensuring patients are emotionally prepared for their journey.